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Table 1 Comparison of L1 Retrotransposition hallmarks across TE types encoded by the L1 ORF2p. PPs consist of both germline (22) and somatic (1) PPs. Hallmarks of Retrotransposition include: insertion length (median length), the percentage of insertions with a detected polyA-tail, polyA-tail median length (bp), target site duplication or deletion (defined as 5–25 bp overlap or distance between insert flanking sequences on the reference), EN cut site (TTTT/A, TTTT/G, TTTC/A) and twin priming events

From: Structural features of somatic and germline retrotransposition events in humans

 

Total (n)

Median length (bp)

Poly-A tail (%)

Poly-A tail median length (bp)

TS duplication (%)

TS deletion (%)

EN cut site (%)

Twin priming rate (%)

somatic L1

1495

394

91.6

39

65.4

8.4

70.1

21.9

germline L1

897

1240

90.7

34

69.5

7.4

63.4

18.4

germline Alu

5936

320

95.1

39

83.8

2.3

62.7

0.02

germline SVA

322

1154

91.3

36

71.7

7.0

69.3

0

PPs

23

1373

95.7

27

69.6

4.3

69.6

13.0