Fig. 1

Landscape of TE expression in SLE. A The flow chart of the analysis describing the study design and the datasets used. B Volcano plot of differentially expressed TEs between SLE patients and healthy controls (Up: 75, Down: 1). FDR < 0.05 and log2 Fold Change > 0.5 were used as cut off to screen differentially expressed TEs. C Heatmap of the 75 upregulated TEs in SLE. The dendrogram showcase the SLE patients can be clustered into two groups. D Pie chart shows the class of the 75 upregulated TEs (LTR: 80%, LINE: 5.33%, DNA: 12%, SINE: 2.67%)