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Fig. 4 | Mobile DNA

Fig. 4

From: Insertion of short L1 sequences generates inter-strain histone acetylation differences in the mouse

Fig. 4

B6-specific L1 insertions associated with MSM-specific H3K9ac peaks. A–G IGV snapshots around L1 insertions. ChIP read densities are shown in pink (B6, two replicates) and light blue (MSM, two replicates). H3K9ac peaks are shown below in purple. Positions of Mb-specific L1 insertions are shown in red. Arrow indicates the direction of L1 and their length is shown in parentheses. H Alignment of the 7 inserted L1 sequences. Only the 3′ region is shown. Numbers in parentheses indicate the lengths of inserted copies. I–K Average ChIP read density of mouse KZFPs, Gm14295 (I), Gm14412 (J), and Gm14436 (K) in regions neighboring short L1Md_Tf copies in mm10 (100–400 bp containing the 3′ end, n = 2424). The ChIP data analyzed for mouse embryonic stem cells were obtained from GEO (accession number, GSE115291). The plots were generated using deepTools

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